Which of the following layers contains interlocking fibrils and is capable of mitosis under friction or pressure?

The correct choice highlights the role of the stratum spinosum, which is a vital layer of the epidermis. This layer is characterized by its interlocking cells that provide structural support and resilience. The "spiny" appearance of this layer comes from the desmosomes connecting the keratinocytes, which are responsible for making the skin strong and flexible.

One of the key features of the stratum spinosum is its capacity for mitosis, particularly in response to friction or pressure. When the skin experiences increased stress or abrasion, the cells in this layer can divide to produce more keratinocytes, which then migrate upward to replace the cells that are lost or damaged at the surface. This regenerative capability is essential for maintaining healthy skin and ensuring barriers against environmental challenges.

In contrast, the stratum granulosum is primarily involved in the process of keratinization, where cells begin to lose their nuclei and cytoplasmic organelles, leading towards their ultimate function in the outer layers. The stratum lucidem, found only in certain areas like the palms and soles, provides additional protection but does not participate significantly in mitosis. The outermost layer, the stratum corneum, is composed of dead keratinized cells that serve