What skin condition consists of plaques or nodules composed of lipid-laden histiocytes?

Xanthomas are skin lesions that appear as plaques or nodules and are characterized by the accumulation of lipid-laden histiocytes, which are a type of immune cell involved in lipid metabolism. These lesions typically form due to persistent high levels of lipids in the blood, associated with conditions like hyperlipidemia, diabetes, or certain genetic disorders. The lipid deposits give xanthomas their distinctive yellow appearance and can occur on various parts of the body, including the elbows, knees, and eyelids.

This condition reflects an underlying issue with lipid metabolism rather than an infectious process, as seen with cellulitis or MRSA, which involve bacterial infections. Blisters, on the other hand, are fluid-filled sacs rather than solid nodules or plaques. Understanding xanthomas aids in recognizing how lipid metabolism disorders can manifest through changes in the skin, emphasizing the connection between systemic health issues and dermatological signs.