What is the role of Langerhans cells in the skin?

Langerhans cells play a crucial role in the immune response of the skin. These specialized dendritic cells are located primarily in the epidermis and are responsible for recognizing and capturing foreign invaders, such as pathogens and allergens. Once they detect these substances, Langerhans cells process the antigens and then migrate to the lymph nodes, where they present the antigens to T-cells, thus initiating an immune response.

Through this process, Langerhans cells act as a critical component of the skin's immune surveillance system, helping to protect the body from infections and other harmful agents that could penetrate the skin barrier. Their ability to detect and respond to foreign invaders makes them an essential part of the skin's defensive mechanisms against various threats.