What is the congenital condition characterized by the absence of pigmentation in the eyes, skin, and hair?

The condition characterized by the absence of pigmentation in the eyes, skin, and hair is known as albinism. This genetic disorder results from a lack of melanin, the pigment responsible for the color of skin, hair, and eyes. Individuals with albinism typically have very light skin and hair, and they may also have vision problems due to a lack of pigmentation in the eyes, which can affect the development of the retina and other structures.

In contrast, vitiligo is a condition where patches of skin lose pigment due to the destruction of melanocytes, but it does not affect the entire body and usually occurs in spots. Papilloma refers to a benign tumor usually associated with the skin or mucous membranes and does not relate to pigmentation. Lentigo is characterized by small, flat, brown spots on the skin due to localized increases in melanin, typically from sun exposure, rather than a complete absence of pigmentation. Hence, albinism is the specific congenital condition that matches the description provided.